Can I play XCOM: Enemy Unknown with a gamepad?

Yes.

The gamepads in the following list have been tested and are supported by XCOM: Enemy Unknown:

• GameStop Gamepad
• GreenAsia USB Joystick
• Jess Tech USB Game Controller
• Logitech Cordless RumblePad 2
• Logitech Dual Action
• Logitech F310 Gamepad
• Logitech F510 Gamepad
• Logitech F710 Gamepad
• Logitech RumblePad 2 USB
• Logitech WingMan Cordless RumblePad
• Moga Pro
• OUYA Game Controller
• Microsoft Xbox 360 wired controller
• Microsoft Xbox 360 wireless controller
• RetroUSB.com RetroPad
• Saitek Cyborg V.1 Game Pad
• SONY PlayStation®3 controller *
• SONY PlayStation®4 controller *
• Thrustmaster 2 in 1 DT
• Thrustmaster Dual Analogue 3
• Thrustmaster Dual Trigger 3-in-1
• Thrustmaster Run N Drive Wireless

* In order to use your PlayStation pad with XCOM: Enemy Unknown, you may need to press the PlayStation button in the center of the controller after connecting the pad to your computer. This allows your computer to recognize the pad.